超声引导下经皮穿刺活检在骨肿瘤术前诊断与治疗中的运用

Application of ultrasound-guided percutaneous biopsy in the preoperative diagnosis and treatment of bone tumors

目的:探讨彩色多普勒超声(彩超)引导经皮穿刺活检在诊断与治疗骨肿瘤中的价值.方法:应用自动活检装置,配合14～18G粗针取材,对64例骨肿瘤患者行彩超检查并引导经皮穿刺活检.所有病例经手术治疗及病理检查证实.结果:(1)彩超引导下自动活检装置并粗针活检,取材成功率为97%(62/64).穿刺活检病理结果与手术后病理检查比较其符合率为97%.(2)所有病例无并发症发生.(3)根据穿刺活检病理结果对33例药物敏感病例术前预防性化疗后手术切除范围均较传统范围缩小.其中26例保住肢体的功能与完整(79%).结论:彩超引导下经皮穿刺活检术对骨肿瘤术前的诊断及治疗方法的选择有重要作用,且具有快速、安全有效的特点.

Objective To investigate the value of color Doppler ultrasonography （CDUS）-guided percutaneous biopsy in the diagnosis and treatment of bone tumors. Methods Ultrasound-guided percutaneous biopsy was performed in 64 patients who was diagnosed by CDUS. Puncture instruments included automatic core biopsy device and 14-18G crude needle. All cases were identified by the operation and pathological examination. Results Tissue-obtained rate was 97% （62/64）. Comparing preoperative pathological diagnosis with postoperative pathological diagnosis, we found the diagnostic correct rate was 97%. No complications resulted from this procedure. According to their pathological results, 33 patients were treated with preoperative chemotherapy. The tumor sizes decreased, and 26 patients saved their limbs and had normal functions. Conclusion CDUS-guided percutaneous biopsy is safe and quick for the preoperative diagnosis and selecting appropriate surgical procedure for bone tumor treatment.