摘要
目的探讨胆石症的形成与垂体肾上腺、甲状腺激素的关系。方法借助放射免疫方法测定了32例(男9例,女23例)胆石症患者血清 ACTH,Cor,TSH,T_3,T_4的含量,并与32例健康献血员对照分析。结果胆结石患者的 Cor 水平与对照组比较(4.54±2.84,3.62±1.06μmol/L,P<0.05)明显升高。T_3水平(0.85±0.35,17.25±0.35pmol/L,P<0.01)明显下降,而ACTH,TSH,T_4无变化。结论胆结石的形成与血清 Cor水平升高,T_3水平降低有关。
AIMS To study the relationship between cholecystolithiasis and alter- ations of some endocrine hormones. METHODS Serum levels of ACTH,corticosteroid(Cor),TSH,T_4 and 5′- T_3 were measured by in 32 patients with cholecystolithiasis and 32 healthy controls. RESULTS The serum level of Cor in patients with cholecystolithiasis was increased significantly compared with that in controls(4.54±2.84 vs 3.62±1.06 μmol/L,P<0.05);and that of T3 in the patients with chole- cystolithiasis was decreased significantly compared with that in the con- trols(0.85±0.35 vs 17.25±0.35 pmol/L,P<0.01).Other endocrine hormones in serum remained normal as in healthy controls. CONCLUSIONS The formation of cholecystolithiasis is related with the in- crease of Cur,and the decrease of T_3 in serum.
