蛋白质组学及其在胰腺癌诊断治疗中的应用
Proteomics techniques and its application in diagnosis and treatment of pancreatic carcinoma
摘要
蛋白质组学的出现为人类全面、深入地了解机体正常或异常生物学功能提供了机会。目前,蛋白质组学在胰腺癌诊断及治疗方面的研究工作中发挥着越来越重要的作用,主要用于发现有早期诊断价值的新肿瘤标志物、明确化疗耐药机制等。
出处
《国外医学（肿瘤学分册）》
2005年第12期936-938,共3页
Foreign Medical Sciences (Cancer Section)
基金
国家自然科学基金资助项目(30371389)
参考文献21
-
1Jain KK. Role of oncoproteomics in the personalized management of cancer. Expert Rev Proteomics,2004,1 ( 1 ) :49-55.
-
2Lawrie LC, Curran S. Laser capture microdissection and colorectal cancer proteomics. Methods Mol Biol,2005 ,293 :245-253.
-
3Ordog T, Redelman D, Miller LJ, et al. Purification of interstitial cells of Cajal by fluorescence-activated cell sorting. Am J Physiol Cell Physiol,2004,286 (2) : C448-456.
-
4Kellner U, Steinert R, Seibert V, et al. Epithelial cell preparation for proteomic and transcriptomic analysis in human pancreatic tissue.Pathol Res and Pract,2004,200(2 ) : 155-163.
-
5Kange R, Selditz U, Granberg M, et al. Comparison of different IMAC techniques used for enrichment of phosphorylated peptides. J Biomol Tech,2005,16(2) :91-103.
-
6Zhou G, Li H, DeCamp D, et al. 2D differential in-gel electrophoresis for the identification of esophageal scans cell cancer-specific protein markers. Mol Cell Proteomics, 2002,1 ( 2 ) : 117-124.
-
7Trakselis MA, Alley SC, Ishmael FT, et al. Identification and mapping of protein-protein interactions by a combination of cross-linking,cleavage, and proteomics. Bioconjug Chem,2005,16 (4) :741-750.
-
8Peri S, Navarro JD, Kristiansen TZ, et al. Human protein reference database as a discovery resource for proteomics. Nucleic Acids Res,2004, ( Database issue) : D497-501.
-
9Oyama T,Osaki T,Baba T,et al. Molecular genetic tumor markers in non-small cell lung cancer. Anticancer Res, 2005,25 ( 2B ) : 1193-1196.
-
10Luo Y, Zhang J, Liu Y, et al. Comparative proteome analysis of breast cancer and normal breast. Mol Biotechnol,2005,29 (3) :233-244.
-
1罗京,张婷,黄卉,杨丹.软骨肉瘤化疗耐药机制[J].实用肿瘤学杂志,2016,30(2):176-179.
-
2郭凯文,唐朝晖,邱文洪,沈关心.Survivin在顺铂诱导Panc-1细胞凋亡中的作用[J].数理医药学杂志,2005,18(2):109-111.
-
3陈欢欢,蔡炜嵩.替莫唑胺治疗多形性胶质母细胞瘤的化疗耐药机制[J].实用药物与临床,2015,18(2):215-219. 被引量：4
-
4张燕,张俐,牛素生,刘俊宁.骨肉瘤化疗耐药机制及逆转治疗的研究进展[J].中国医药导报,2012,9(32):23-25.
-
5张伟,孙丽娟,林钊宇,范松,郑倩琪,李劲松.微小RNA-15b及其靶蛋白BMI1的表达与舌鳞癌患者化疗耐药、预后的关系[J].中国口腔颌面外科杂志,2012,10(6):454-460. 被引量：2
-
6陈烨.反义核酸技术在白血病研究中的进展[J].国外医学（输血及血液学分册）,1997,20(2):81-85.
-
7梁志清.卵巢癌化疗耐药机制研究进展[J].中国实用妇科与产科杂志,2005,21(7):446-448. 被引量：3
-
8冯继良,吴强.恶性卵巢肿瘤化疗耐药机制及逆转的研究进展[J].临床肿瘤学杂志,2003,8(4):305-308. 被引量：2
-
9陈瑾,张树荣,乐杰.卵巢癌铂类药物化疗耐药机制研究进展[J].中国热带医学,2007,7(10):1895-1897. 被引量：2
-
10刘君,何嘉曦,马文超,刘翔,李慧灵,何建行.不同肺腺癌细胞系对不同化疗药物的反应及与EMT相关性研究[J].健康导报（医学版）,2014,19(8):8-9.
