摘要
The biomimetic coating process in comparison with other processes is reviewed. This processing shows advantages in the surface bio-modification, such as low cost and flexible processing, wide range of apatite composition and thickness, non-line-of-sight characteristic and possibility to coat polymers and porous implants. The (bio-)(mimetic) apatite coating is made up of larger number of globules with size of 15μm. Each globule is a group of (numerous) flakes with a size range of 100200nm to 30μm in length and 0.11μm in thickness. In-vitro and (in-vivo) studies show that the biomimetic apatite coating can promote an early and strong bonding to bone or promote the bone in-growth into the porous structure, which will be beneficial to the cementless stable fixation of orthopaedic implants. Recently developed co-precipitation of a kind of protein molecules into the HA coating shows much (promising.)
The biomimetic coating process in comparison with other processes is reviewed. This processing shows advantages in the surface bio-modification, such as low cost and flexible processing, wide range of apatite composition and thickness, non-line-of-sight characteristic and possibility to coat polymers and porous implants. The biomimetic apatite coating is made up of larger number of globules with size of 1 - 5μm. Each globule is a group of numerous flakes with a size range of 100 - 200 nm to 30 μm in length and 0. 1 - 1 μm in thickness. In-vitro and in-vivo studies show that the biomimetic apatite coating can promote an early and strong bonding to bone or promote the bone in-growth into the porous structure, which will be beneficial to the cementless stable fixation of orthopaedic implants. Recently developed co-precipitation of a kind of protein molecules into the HA coating shows much promising.
出处
《中国有色金属学会会刊:英文版》
CSCD
2005年第6期1199-1205,共7页
Transactions of Nonferrous Metals Society of China
关键词
羟基磷灰石
生物材料
仿生涂层
磷酸钙
表面改性
hydroxyapatite coating
biomedical application
biomimetic coating
biometallic materials
surface modification