摘要
小儿下颌骨郎格汉斯组织细胞增生症在临床上非常少见,作者报道1例收治病例,并结合有关文献资料对其临床表现、影像学表现、病理诊断及鉴别诊断、治疗方案进行讨论。认为小儿下颌骨郎格汉斯组织细胞增生症少见,且临床表现不典型,也无特征性的影像学表现,确诊只能依靠病理检查。郎格汉斯细胞增生是其特征性镜下改变,S-100和CD1a的免疫组织化学检查有助于诊断和鉴别诊断,其治疗以尽早手术切除结合密切随访为主。
Langerhans' cell histiocytosis of the mandible is a rare disease in infant. This article reported a case of Langerhans' cell histiocytosis of mandible in a 2-year old female child. The clinical manifestation, radiographic characteristics, pathologic diagnosis, differential diagnosis and treatment were discussed. It is concluded that Langerhans' cell histiocytosis of the mandible in infant is rare without typical clinical manifestation and radiographic characteristics; final diagnosis is based on pathological examination with the characteristic hyperplasia of Langerhans' cell; immunohistochemistry examination of S-100 and CDIa are useful for diagnosis and differential diagnosis. Surgical resection with close postoperative follow-up is suggested as the main treatment for this disease.
出处
《上海口腔医学》
CAS
CSCD
2005年第6期664-666,共3页
Shanghai Journal of Stomatology