Tei指数评价2型糖尿病患者心功能的临床研究

Estimation of Qobal Function of Left Ventricular by Tei Index in Patients with Type 2 Diabetes Mellitus

目的:探讨Tei指数评价2型糖尿病患者心功能变化的临床价值。方法:2型糖尿病患者45例,正常对照组30例。行常规超声心动图检查测量左室舒张末期内径和收缩末期内径(LVDd,LVDs)。二尖瓣口血流图舒张早期和舒张晚期血流峰值之比(E／A)、E 峰减速时间(DT)、左室等容舒张时间(IVRT)、肺静脉血流图收缩波和舒张波之比(S／D)以及Tei指数。结果:2型糖尿病组的DT及 Tei指数较正常组延长(202．04±40．51 ms和184．92±43．60ms,P<0．01)(0．68±0．22和0．54±0．15,P<0．01)。结论:Tei指数能简便、敏感、综合评价心脏的整体收缩舒张功能,有助于早期发现2型糖尿病患者左室舒张功能障碍。

Objective： To investigate the value of Tei index of estimating left ventricular global function in patients with type 2 diabetes mellitus. Methods： The study population included 45 patients with type 2 diabetes mellitus （group A） and 30 normal control subjects（group B）. The systolic and diastolic diameters of left ventricular（LVDd, LVDs）, E/A ratio （E/A）, deceleration time （DT）, isovolume relaxation time （IVRT）, S/D ratio （S/D） and Tel index were measured. Results： DT and Tei index in group A were prolonged than those in group B （202.04 ± 40. 51 ms vs 184. 92 ± 43. 60 ms ,P〈0. 01 ; 0. 68 ± 0. 22 vs 0. 54 ± 0. 15 ,P〈0. 01 ）. Conduslon： Tel index is valuable sensitive and easy for estimating the combined systolic and diastolic function of left ventricule with type 2 diabetes mellitus.