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血清血管内皮生长因子测定对消化系统恶性肿瘤的诊断价值 被引量:1

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摘要 采用酶联免疫吸附法(ELISA法)检测150例消化系统疾病患者血清中VEGF、CEA含量。探讨血清血管内皮生长因子(VEGF)测定在消化系统恶性肿瘤诊断中的价值以及联合检测癌胚抗原(CEA)的临床意义。结果:消化系统恶性肿瘤患者血清VEGF含量明显高于良性疾病及正常对照者(P<0.01),恶性肿瘤伴转移患者血清VEGF含量与无转移患者相比较有明显升高(P<0.05),联合检测患者血清VEGF和CEA,其诊断恶性肿瘤的敏感性较单独检测血清CEA有明显提高,差异有显著性(P<0.05)。提示血清VEGF测定有助于消化系统恶性肿瘤的临床诊断及预后判断,联合检测血清VEGF和CEA对消化系统恶性肿瘤的诊断有临床实用价值。
出处 《苏州大学学报(医学版)》 CAS 北大核心 2005年第6期1114-1115,共2页 Suzhou University Journal of Medical Science
基金 江苏省135重点人才课题资助(编号:37RC2002037)
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