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替代终点在心血管病临床试验中的运用及其局限性 被引量:2

The Use and Limitation of Surrogate End Points in the Cardiovascular Diseases Clinical Trials
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作者 方向华
出处 《循证医学》 CSCD 2005年第6期364-367,共4页 The Journal of Evidence-Based Medicine
关键词 替代终点 临床试验 心血管病 surrogate end point clinical trial caidiovascular diseases
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参考文献31

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共引文献11

同被引文献26

  • 1王树堂,周岱翰.对于目前恶性肿瘤临床疗效评价标准的评价[J].天津中医药,2004,21(4):277-280. 被引量:14
  • 2郭新峰,朱泉,赖世隆.替代指标和中间指标及其在中医药疗效评价研究中应用价值的思考[J].中国中西医结合杂志,2005,25(7):585-590. 被引量:56
  • 3魏华凤,郑培永,季光.中医临床疗效评价的思路与方法[J].中西医结合学报,2005,3(3):184-190. 被引量:32
  • 4徐小国,蒋萌.替代指标在临床试验中的应用与局限性[J].中国临床药理学与治疗学,2006,11(10):1194-1197. 被引量:22
  • 5Bucher HC,Guyatt GH,Cook DJ,Holbrook A,McAlister FA.Users'guides to the medical literatrue:XIX.Applying clinical trial results.A.How to use an article measuring the effect of an intervention on surrogate end points[J].JAMA,2000; 19:192 -7
  • 6Stuart G.Baker.Surrogate Endpoints:Wishful Thinking or Reality[J]? J Nall Cancer Inst,2006;98:502-3
  • 7Susan S.Ellenberg surrogate endpoints:the debate goes on[J].Pharmacoepidemiol Drug Safety,2001; 10:493-6
  • 8Tseng LN,Sheu WH,Ho ES,Lan HH,Hu CC,Kao CH.Effects of alendronate combined with hormone replacement therapy on osteoporotic postmenopausal Chinese women[J].Metab Clin Exp,2006;55:741-7
  • 9Collins R,Peto R,MacMahon S,Hebert P,Fiebach NH,Eberlein KA,et al.Blood pressure,stroke,and coronary heart disease.Part 2,Short-term reductions in blood pressure:overview of randomized drug trials in their epidemiological context[J].Lancet,1990;335:827-38
  • 10SHEP Cooperative Research Group.Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension:final results of the systolic hypertension in the elderly program (SHEP)[J].JAMA,1991; 265:3255-64

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