3-羟基丙醛加氢制1,3-丙二醇反应条件的考察

Preparation of 1,3-propanediol by Hydrogenating 3-hydroxypropanal

以丙烯醛水合产物3-羟基丙醛（HPA）水溶液为原料，在Ni／SiO2／Al2O3催化剂作用下与高压氢气反应生成1，3-丙二醇（1，3-PDO）。实验结果表明：1，3-PDO收率随温度的升高而提高，但反应温度不宜超过70℃；随氢气压力的升高而提高，在4．0～7．0MPa范围内呈线性升高关系；随空速的增加而降低，在2．25～6．75h^-1范围内呈线性下降关系。正交实验得到较佳反应条件为：反应温度为50℃、压力为7．0MPa、空速为2．25h^-1，其中空速为最主要影响因素。

1,3 - propanediol was prepared by hydrogenation of 3 - hydroxypropanul aqueous solution over Ni/SiO2/Al2O3 catalyst under high pressure. The results of experiments showed that the yield of 1,3 - PDO increased with elevation of temperature, but which should not exceed 70℃ ; It increased by hydrogen pressure, and the relationship was linear in the range of 4.0 -7.0 MPa; It decreased with increase of LHSV, and the relationship was linear in the range of 2.25 - 6.75 h^- 1. The appropriate reaction conditions from orthogonal experimental design were as follow ： reaction temperature 50℃, hydrogen pressure 7.0 MPa, LHSV 2.25 h^-1. LHSV was the most primary factor among the reaction conditions.