血清-腹水清蛋白浓度梯度与腹水胆固醇在腹水鉴别诊断中的意义

Significance of serum-ascites albumin gradient and ascites cholesterol in differential diagnosis of ascites

目的研究血清-腹水清蛋白浓度梯度(SAAG)及腹水胆固醇在肝性腹水和非肝性腹水鉴别诊断中的价值。方法选择腹水患者86例,其中肝性腹水52例,非肝性腹水34例。采用全自动生化分析仪测定血清和腹水清蛋白及胆固醇,SAAG值为血清清蛋白与腹水清蛋白值之差。结果肝性腹水组SAAG为(18.46±8.67)g/L,非肝性腹水组为(8.33±3.61)g/L,两者比较,差异有显著性(P<0.01);92.31%的肝性腹水患者SAAG>11g/L,而非肝性腹水患者均<11 g/L。肝性腹水组腹水胆固醇为(0.34±0.23)g/L,非肝性腹水组为(0.82±0.31)g/L,两者比较,差异有显著性(P<0.01);肝性腹水组腹水胆固醇<0.55 g/L者占88.46%,而非肝性腹水组均>0.55 g/L。结论SAAG及腹水胆固醇检测在肝性和非肝性腹水鉴别诊断中有重要价值。

Objective To study the significance of serurn-ascites albumin gradient （SAAG） and ascites cholesterol in differential diagnosis between hepatogenie and non-hepatogenie ascites. Methods Eighty-six patients with ascites （52 with hepatogenie ascites and 34 with non-hepatogenie aseites） were chosen as study subjects. Autobiochemieal analysis system was applied to detect serum and ascites albumin and cholesterol. SAAG value were calculated. Results SAAG in hepatogenie aseites group and non-hepatogenie group were （ 18.46 ± 8.67） g/L and （8.33 ± 3.61 ） g/L, respectively. There was significant difference between two groups （ P 〈0.01）. SAAG of 92.31% of hepatogenie aseites patients were 〉11 g/L, and SAAG of all non-hepatogenie aseites patients were 〈 11 g/L. Aseites cholesterol in hepatogenic aseites group and non-hepatogenie ascites group were （0.34 ± 0.23） g/L and （0.82 -± 0.31） g/L respectively （ P 〈 0.01 ）, ascites cholesterol in 88.46% of hepatogenie ascites group were 〈0.55 g/L, and ascites cholesterol in all non-hepatogenie ascites patients were 〉0.55 g/L. Conclusion There are important significance of SAAG and ascites cholesterol in differential diagnosis between hepatogenie and non-hepatogenie ascites.