慢性丙型病毒性肝炎患者医院感染调查研究

Investigation on nosocomial infection in patients with chronic hepatitis C

目的调查慢性丙型病毒性肝炎患者医院感染情况及其危险因素。方法对2001年7月-2004年7月间189例住院慢性丙型肝炎病毒(HCV)感染患者的临床资料进行回顾性分析。结果189例慢性HCV感染患者医院感染率为21.69%;感染部位以腹腔(41.46%)和呼吸道(26.83%)为主;慢性丙型重型肝炎患者医院感染率为58.14%,慢性丙型重、中、轻度肝炎患者医院感染率分别为21.57%,7.55%,2.38%;导尿和腹水蛋白≤10 g/L是其医院感染危险因素。结论慢性丙型病毒性肝炎患者医院感染率高,且病程越长,病情越重,处于危险因素中,医院感染率越高。

Objective To study the occurrence and risk factors of nosocomial infection （NI） in patients with chronic hepatitis C. Methods Clinical data of 189 hepatitis C patients who were hospitalized from July 2001 to July 2004 were surveyed retrospectively. Results NI rate in patients with chronic hepatitis C was 21.69%, the abdominal cavity （41.46%） and respiratory tract （26.83%） were the main infection sites. NI in patients with chronic hepatitis C gravis, severe chronic hepatitis C, moderate hepatitis C and mild hepatitis C was 58.14%, 21.57%, 7.55% and 2.38% respectively. Urethral catheterization and ascites albumin 410 g/L were risk factors for NI. Conclusion The high NI rate in patients with chronic hepatitis C is related with long periods of hospitalization, the severity of the illness and risk factors.