原发性膀胱类癌的诊治分析(附5例报告)

Diagnosis and treatment of Primary carcinoid tumor of theurinary bladder (report of 5 cases)

目的:探讨原发性膀胱类癌的临床特征及诊断治疗方法。方法:回顾分析5例原发性膀胱类癌的病理资料。临床症状主要表现为无痛性肉眼血尿,但无类癌综合征表现。膀胱镜检均发现息肉样新生物,尿液脱落细胞检查癌细胞阳性1例。结果:5例患者中1例行根治性膀胱切除术,回肠代膀胱辅以化疗;2例膀胱部分切除术:2例经尿道电切除术。3例分别于5年、3年和6个月死于肿瘤转移;2例分别随访8年、1年未见复发及转移。结论:原发性膀胱类癌无明显特异性症状,确诊需靠组织病理学检查。手术切除是治疗本病的主要方法。膀胱类癌的预后差。

Objective： To study the clinicopathological characteristics, diagnosis, treatment and proghosis？ of carcinoid tumor of the urinary bladder. Methods： The clinical and histopathologic data of five careinoid tumor of the urinary bladder were retrospectively analysed. There were four male patients and one female with an？ median age of six - one. All patients presented with gross hematuria, but with no careinoid syndrome. Cystoscopies showed sessile polypeid masses. Results： Among of them, one patient received radical systectomy followed by radiotherapy, two patients received partial systectomy, and others received transurethral resection. Three patients died of the tumor meeastasis at survival interval five years, three years and six months, respectively; other two patients were still alive eight years and one years following the surgical treatment. Conclusions： The primary carcinoid tumor of the urinary bladder has no specific symptoms,the diagnosis depends on histopathological tests. Surgical intervention is the mainstay to treat the disease, but the prognosis is poor.