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氟甲喹(Flumeguine)毒性研究 被引量:2

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摘要 氟甲喹(Flumeguine)毒性研究徐士新(中国兽药监察所北京,100081)氟甲喹(Flumequine)为第一代喹诺同类合成抗菌药,白色细微结晶,无昧,不溶于水,可溶于碱性水溶液中。它通过破坏DNA-旋转酶而抑制核酸的合成,从而阻止菌细的繁殖。...
作者 徐士新
机构地区 中国兽药监察所
出处 《中国兽药杂志》 北大核心 1996年第1期24-27,共4页 Chinese Journal of Veterinary Drug
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同被引文献22

  • 1李剑勇,鲁润华.动物用氟喹诺酮类药物的研究进展概况[J].中兽医医药杂志,2004,23(6):19-23. 被引量:28
  • 2梁增辉,林黎明,刘靖靖,江志刚,宫庆礼.噁喹酸和氟甲喹在鳗鱼体内的药代动力学研究[J].海洋水产研究,2006,27(3):86-92. 被引量:22
  • 3Palominos R, Freer J, Mondaca M A, et al. Evidence for hole participation during the photocatalytic oxidation of the antibiotic flumequine[J]. Journal of Photochemistry and Photobiology A: Chemistry, 2008, 193 : 139 - 145.
  • 4Nieto J, Freer J, Contreras D, et al. Photocatalyzed degradation of flumequiue by doped TiO2 and simulated solar light [J]. Journal of Hazardous Materials, 2008, 155 ( 1 - 2) :45 - 50.
  • 5Lai H T, Lin J J. Degradation of oxolinic acid and flumequine in aquaculture pond waters and sediments [ J]. Chemosphere, 2009, 75 (4) :462 - 468.
  • 6Williams A J, Deck J, Freeman J P, et al. Biotransformation of flumequine by the fungus Cunninghamella elegans[J]. Chemosphere, 2007, 67 (2) :240 - 243.
  • 7MARTINSEN B, HORSBERG T E. Comparative Single-Dose Pharmaco-Kinetics of Four Quinolones, Oxolinic Acid, Flumequine, Sarafloxocin and Enrofloxacin in Atlantic salmon (Salmo salar) Held in Seawater at 10 ℃ [J]. Antimi- crob. Agents Chemother, 1995, 39(5): 1059-1064.
  • 8ELEMA M O, HOFF K A, KRISTENSEN H G. Bioavailability of Flumequme After Oral Administration to Atlantic salmon (Salmosalar L. ) [J]. Aquaculture, 1995, 136: 209-219.
  • 9SAMUELSEN O B, ERVIK A. A Single Dose Pharmacokinetic Study of Flumequine After Intravenous, Intraperitoneal and Oral Administration to Atlantic halibut (Hippoglossus hippoglossus) Held in Seawater at 9 ℃[J]. Aquaculture, 1997, 158: 215-227.
  • 10PLAKAS S M, SAID K R, MUSSER S M. Pharmacokinetics, Tissue Distribution, and Metabolism of Flumequine in Channel Catfish (Ictaluruspunctatus) [J]. Aquaculture, 2000, 187(1): 1-14.

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