颈动脉内膜-中层厚度与冠心病危险因素间的关系

Association of Coronary Artery Disease risk factors with Intima-media Thick of the Common Carotid Artery

目的探讨颈动脉内膜-中层厚度(IMT)与冠心病(CAD)危险因素间的关系。方法可疑或确诊CAD患者104例,入院时均应用超声技术测量双侧颈总动脉远端的IMT,同时检测CAD 危险因子年龄、性别、吸烟情况、收缩压、舒张压、脉压、空腹血糖、甘油三脂、总胆固醇、高密度脂蛋白、低密度脂蛋白(LDL-C)、血尿酸值。数据采用SPSS10．0统计学软件进行多因素回归统计分析。分析颈总动脉IMT(CCIMT)与CAD危险因素之间的关系。结果平均CCIMT与CAD危险因素的关系,在排除混杂因素后,与年龄、吸烟、脉压差、高LDL-C及高尿酸呈显著相关(P<0．001),而与高甘油三脂、高总胆固醇、低高密度脂蛋白及血糖异常无显著相关。结论 CCIMT的增加与冠心病危险因素直接相关。超声测定颈动脉IMT可作为预测CAD的非侵入性检查手段。

Objective To study the association of risk factors of coronary artery disease （CAD） with intima-media thick （IMT） of the common carotid artery. Methods 104 patients with suspected CAD or CAD were selected. The IMT of the common carotid arteries were measured in all patients with Echo and the risk factors of CAD were measured Results Age, smoking, pulse pressure, high LDLC and high uretic acid were significantly association with average of common carotid IMT in patients with CAD. Conclusion IIMT of the common carotid artery are related with risk factors of CAD. IMT of carotid artery measured with Echo are an important noninvasive tool for the prediction CAD.