卵巢恶性肿瘤经阴道超声定量指标与临床分期的相关性研究

A Correlative Study between Quantitive Indices of Transvaginal Ultrasonography and Clinical Stages on Malignant Ovarian neoplasms

目的评价经阴道超声定量指标与卵巢恶性肿瘤临床分期的关系。方法术前应用经阴道彩色多普勒超声(Transvaginal color doppler ultrasonography,TVCDU)与三维彩色血管能量成像(Three-d imensional color power an-giography,TR3D-CPA)检测38例卵巢恶性肿瘤患者,测定肿瘤血流阻力指数(Resistance index,R I)与血管指数(Vasculary index,VI),分析R I、VI与临床分期的关系。结果38例卵巢恶性肿瘤患者R I为(0.44±0.13),VI为(0.08±0.052)条/cm3。Ⅰ、Ⅱ期与Ⅲ、Ⅳ期肿瘤的R I、VI间的差别均有显著性意义(P<0.05)。结论R I随临床分期的升高而降低,VI随临床分期的升高而升高。R I与VI可于术前评价卵巢恶性肿瘤的血管生成,为术前诊断及预后评估提供有价值的信息。

Objective To evaluate the correlations between quantitive indices of transvaginal ultrasonography and clinical stages of malignant ovarian neoplasms. Methods 38 malignant ovarian neoplasms patients were examined preoperatively by transvaginal three - dimensional color power angiography （TR3D - CPA） and transvaginal color Doppler uhrasonography （TVCDU）. Resistance index （RI） and vasculary index （VI） were detected quantitatively. The relations between the indices （RI and VI） and clinical stages were also analyzed. Results RI in 38 malignant ovarian neoplasms patients was （0. 44 ± 0. 13） , VI was （0. 08 ±0. 052） eounts/cm^3. There were significant differences in VI and RI between stage Ⅰ , Ⅱ and Ⅲ, Ⅳ （ P 〈0. 05）. Conclusion The higher the stage was, the lower RI was and the higher VI was. RI and VI can evaluate the angiogenesis of malignant ovarian neoplasms before operation, which can provide valuable information to diagnose preoperatively and predict prognosis.