放射性核素骨显像与X线平片对前列腺癌骨转移的诊断分析

Diagnostic Analysis of Radionuclide Bone Imaging and X-ray Film for Bone Metastasis of Prostate Cancer

目的:探讨核素骨显像与X线平片对前列腺癌骨转移的诊断意义。方法:对59例前列腺癌患者静脉注射99Tcm-MDP 925 MBq^1 110 MBq行SPECT全身骨显像和X线平片检查,观察全身骨骼放射性分布情况并与X线检查对比分析。结果:骨显像发现30例骨转移瘤,阳性率90.9%。其中无骨痛患者发生骨转移14例,占46.7%。4例为单发转移,占13.3%。26例为多发转移,占86.7%。X线发现21例,阳性率63.6%。二者符合率为66.7%。结论:核素骨显像有早期诊断前列腺癌骨转移灶的价值。两种方法结合应用对前列腺癌骨转移的诊断有互补作用,可以提高诊断率。

Objective To evaluate the diagnostic significance of radionuclide bone imaging and plane X-ray bone imaging for skeletal metastasis of prostate cancer. Methods 59 patients with prostate cancer were injectcd intravenously^99Tcrn-MDP 925 MBq-1110 MBq and examined to observe radiodistribution of whole body in skeletal metastases with whole body imaging and plane X-ray film and compare the two methods. Results The 30 patients were detectedmetastases tumor in bone. The positive rate was 90.9%. The 14 （46.7%） painless patients were discovered （46. 7%）. Single metastasis lesion and multimetastases were found in 4 （13. 3%） and in 26 （86. 7%） patients respectively. 21 skeletal metastasis patients were detected by the plane X-ray film method. The positive rate was 63. 6%. Comparing the two methods,the accordance was 66. 7%. Conclusion The results show that Radionuclide bone imaging can find the skeletal metastasis earlier than that of the X ray film in patients with prostate cancer. Combining of the two methods is useful to improve accuracy of the diagnosis.