WS-频谱仪对腹膜透析的影响

THE EFFECT OF BFS ON PERITONEAL DIALYSIS PATIENTS

目的:对16例慢性肾功能衰竭(CRF)接受持续性不卧床腹膜透析(CAPD)治疗的患加用WS-频谱仪照射治疗7～10天,在自身条件相同的情况下进行治疗前后对比。结果:腹膜对Cr、B显著增加(P均<0.05),甲襞微循环明显改善,红细胞电泳时间缩短,外周血总T细胞(CD_3)显著上(?)辅助/诱导细胞亚群(CD_4)略上升,T抑制/细胞毒亚群(CD_8)下降。CD_4/CD_8值显著升高(P<0.00谱仪具有改善微循环,提高腹膜透析效能。调节免疫功能的作用。

Objective： We achiveed better effect in the treatment of chronic renal failure （CRF） during continuous ambulatory peritoneal （CAPD） by using BFS. Patients and methods： 16 Patients with CRF during CAPD, 5 males and 11 females, aged 38-67 years （average 54） .The Patients had no peritonitis for more than 3 months and were treated with CAPD from 2 to 34 months, average 10.94 months, no changes were made in diet or medication therapy for 1 weeks prior the use of BFS as basic control group and during the whole course of the use of BFS. 20 minutes after per CAPD per/usion.Patients were irradiated by two BFS at low grade. One （101D type） directed to the abdomen and the other （301 c type） to the bilateral yungchan points for 30 minutes, 4 times a day for 7 - 10 days. per/using and draining speed of the dialytic fluid, either was kept at 100 ± 20ml/min, samples of blood and dialytic fluid of the basic control group and the using BFS group were analyzed for the urea nitrogen （UN）, Creatinine （CR）, Na^＋, middle molecule substances （MMS） and the total protein （TP） mean clearance was calculated and compared, time of erythrocytes electrophoresis, immunoglobulin and nailfold microcirculation （examined with Xi - guang brand microcirculation TV - computer measure system, MCX-5 type） were examined in 16 patients Tcell subgroups （CD3、 CD4、 CD5） in peripheral blood （examined with EPICSV, Coulter, Corp. U. S. A） were assayed in 8 patients. Results： The peritoneal eliminate rates for Cr, UN, and Na ＋ were increased significantly （ P〈 0.05）, but for MMS and TP were not increased significantly （ P 〉 0.05） ; The TP of the plasma was raised greatly （ P〈 0.01 ） . Time of erythrocytes alectrophorasis was shortened （ P 〈 0.05 ） . patients peripheral bolld total T cells （CD3） were raised significantly （P〈0.05） .THE TP of the plasma was raised greatly （P〈0.01） .Time of ery. throcytes electrophoresis was shortened （P〈 0.05 ） . patients peripheral blood total T cells （ CD3 ） were raised significantly （P 〈 0.01 ）, helper T cell （CD4） . were raised slightly, suppressive/eytotoxic T cells （CD5） were reduced. Ratio of CD4/CDs was raised significantly （P〈 0.01 ） . Patients had sideeffect during BFS irradiation. Conclusion; These results suggest BFS has the effect on improving microculation. Raising efficiency in peritoneal dialysis and regulating immune function.