屈反射与痛阈量化测定

Nociceptive Flexion Reflex and Quantified Objective Pain Threshold Measurement

目的对人的痛阈进行客观量化测定。方法利用人类感痛性屈曲反射（ＮＦＲ）阈值与痛阈的密切关系，应用电子刺激系统与肌电记录系统建立ＮＦＲ痛阈测定法，对３２名正常人进行主观痛阈、ＲⅡ及ＲⅢ反射阈的测定。结果正常人的ＲⅡ反射阈为５．５２±０．７２Ｖ，主观痛阈为６．７２±１．１６Ｖ，ＲⅢ反射阈为７．３４±１．２１Ｖ。在痛阈与ＲⅢ反射阈之间存在密切相关关系（ｒ＝０．９２９８）。结论可用ＲⅢ反射阈来客观反映主观痛阈，使疼痛的研究具有量化指标。

Objective To measure the quantified objective threshold of pain in human.Methods According to the close correlation between the threshold of nociceptive flexion reflex(NFR)and the subjective pain threshold, the subjective pain threshold,R Ⅱ and RⅢresponses in 32 normals were measured using electronic stimulator and EMG instruments.Results The threshold of R Ⅱ response in normals was 5. 52±0.72 V,the threshold of R Ⅲ response was7. 34±1.21 V and the subjective pain threshold was 6.72 ±1. 16 V. The statistics showed very close correlation(r=0. 9298)existing between the threshold of RⅢ response and the subjective pain threshold. Conclusion This method is practicable,the threshold of RⅢ response can provide a quantified objective index in pain research.