摘要
本文研究了以溴代琥珀酰亚胺(NBS)为氧化剂的(131)Ⅰ标记肝癌单克隆抗体HAb18F(ab’)2的方法。探讨了反应体系中NBS的用量,F(ah’)2的用量及Na(131)Ⅰ活度三个因素对标记率的影响,并从反应机理上予以解释。
A N-bromosuccinimide (NBS) oxidant method for labeling F (ah' )2 fragments ofMcAb HAb18 by radioiodine-131 was described. The effects of NBS concentration, F (ah' )2concentration and Na131I activity on labeling efficiency were studied.
出处
《细胞与分子免疫学杂志》
CAS
CSCD
1996年第2期28-30,共3页
Chinese Journal of Cellular and Molecular Immunology