60例系统性红斑狼疮、皮肌炎微量蛋白尿检测及其意义

CLINICAL VALUE OF MICROALBUMINURIA MEASUREMENT IN 60 CASES OF SLE AND DERMATOMYOSITIS

用一次尿蛋白／肌酐（ｐｒ／Ｃｒ比值）检测６０例系统性红斑狼疮（ＳＬＥ）和皮肌炎（ＤＭ）患者尿的微量蛋白。结果，尿蛋白定性阳性者，（Ｐｒ／Ｃｒ比值均升高；尿蛋白定性阴性的ＳＬＥ１０例及ＤＭ２２例中的１４例ｐｒ／Ｃｒ比值也升高。研究提示，尿Ｐｒ／Ｃｒ比值检测与尿蛋白定性试验的结果相符，且较后者更敏感，可用于结缔组织病早期肾脏损害的诊断。

his paper reported the microalbtuminuria was mezestired in 60 cases of system lupus erythematosu(SLE)anddennatomyositis by using urinary pnjtein to creatinine rtio(Pr/ Cr)in a single voided urine sample. The resultsshowed the patients with clinical positive proteinuria had a significatnt elevated Pr/Cr.All SLE and 14/22 cases ofdennatomyositis with clinical negative proteinuria had also elevated Pr/Cr.The tudy suggested that the result of Pr/Cr measure was much correspondent with the one of proteinuria qualitative test and this method of Pr/Cr measure isa more sensitive indicator than proteinuria qualitative test for the early diagnosis of renal damage in the connective tissue diseases.