海藻酸钠微球血管栓塞剂治疗子宫腺肌病的疗效分析

Efficacy analaysis of sodium alginate(KMG) in the treatment of adenomyosis

目的研究海藻酸钠微球血管栓塞剂(KMG)在子宫动脉栓塞术(UAE)治疗子宫腺肌病的近期临床疗效.方法 40例子宫腺肌病患者均采用4F Cobra导管经皮股动脉穿刺双侧子宫动脉超选择插管,至双侧子宫动脉远段,用500～700 μm海藻酸钠微球栓塞.结果 40例海藻酸钠微球栓塞病例,1～3个月后35例痛经症状消失,5例明显改善;38例栓塞后1～3个月后月经量显著减少,月经量平均减少56.2%,2例栓塞后3个月恢复正常;32例贫血患者,栓塞后3～6个月复查血红蛋白含量均恢复正常.术后6个月B超示子宫、病灶体积缩小47.3%～61.4%.无严重并发症发生.结论海藻酸钠微球血栓塞剂是治疗子宫腺肌病安全有效的治疗方法.

Objective To study the efficacy and side effects of sodium alginate（KMG） ,a new embolis mic agent used in uterine artery embolism（UAE） for treating adenomyosis. Methods UAE was performed in 40 patients with adenomyosis. 4F Cobra catheter was inserted into uterine arteries. KMG with a diameter of 500 - 700μm was used to embolize the arteries. Results The complete emission of dysmenorrhea was found in 35 patients using KMG,after 1-3 months partial remission in 5 cases; The menstrual volume was reduced 56,2 % after 1- 3 months in 38 cases in average, 2 cases returned to normal after 3 months of therapy. In 32 patients with anemia, Hb was returned to normal volue after 3-6 months, after UAE using KMG, the bodies of uterus and the lesions were reduced about 47.3% - 61.4 % in 6 months. No serious complications occurred in all patients. Conclusion Embolis mic agent KMG used in UAE for adenomyosis is safe and effective, but further observation is needed to determine its longterm effectiveness.