婴幼儿先天性心脏病合并室缺的肺动脉压测定研究

Doppler echocardiography prediction of pulmonary artery pressure in young children with isolated ventricular septal defect

目的探讨婴幼儿先天性心脏病合并室缺的肺动脉压测定与连续波多普勒法相关性的临床研究。方法40例婴幼儿先天性心脏病合并室缺患者分为两组,以室缺合并平均肺动脉压>20 mm Hg为观察组,室缺合并平均肺动脉压<20 mm Hg为对照组,应用连续波多普勒法与术前用导管法所测肺动脉压进行比较。结果观察组连续波多普勒法测出肺动脉压与导管所测肺动脉压显著相关(r=0.70,P<0.01),可达到定量诊断肺动脉高压的目的;对照组不紧密相关(r=0.65,P>0.05)。结论连续波多普勒法对婴幼儿先天性心脏病合并室缺的患儿的肺动脉压评估可靠。

Objective The purpose of this study was to evaluate the predictive value of Doppler echocardiography for assessment of PAP in young children with isolated ventricular septal defect. Methods After reviewed clinical history and echocardiogram of 40 cases,we evaluated the correlation between Doppler echocardiography and right heart catheterization in young children with isolated ventricular septal defect. Young children with mean PAP 〉 20mmHg（group 1 ） and those with mean PAP 〈 20mmHg（group 2）, respectively, underwent right heart catheterization and Doppler eehocardiography, and their results of PAP were compared. Results The data resulted from Doppler echo were obviously correlated with those of RHC（ r = 0.75, P 〈 0.01 ） in group 1. Conclusion Doppler echocardiography is a reliable and noninvasive method for assessing pulmonary artery hypertension in young children who were suffering from isolated ventricular septal defect accompany those mean PAP 〉20mmHg. However,the direct measurement of PAP by cardiac catheterization is still required when there are conflicting noninvasive data in young children with isolated ventricular septal defect and accompany mean PAP 〈 20mmHg.