血清与胸水癌胚抗原检测对良恶性胸腔积液的诊断价值

The assays of tumor marker CEA for differential diagnosis of pleural effusion

目的探讨胸腔积液患者胸水与血清的癌胚抗原(CEA)水平及其比值对良恶性胸腔积液的诊断价值。方法采用放射免疫分析法分析88例胸腔积液患者胸水与血清CEA水平及比值,其中恶性胸腔积液患者30例,良性胸腔积液患者44例。结果恶性组患者胸水与血清的CEA水平及其比值均明显高于良性组,两组差异有显著意义(P<0.01)。结论检测患者胸水与血清CEA水平及其比值有助于临床胸水性质的诊断。

Objective To study the clinical significance of tumor marker CEA in the differential diagnosis of pleural effusion. Methods 88 serum and hydrothorax samples were collected from 88 in-patlents with pleural effusion. Among them,30 patients were suffered with malignant pleural effusion and 58 patients with benign pleural effusion. The concentration of CEA was determined by immunoradiometric assay, Results The positive rate of serum and hydrothorax CEA in malignant group were significantly higher than that in benign pleural effusion（P〈 0.01）. Conclusion Tumor marker CEA has high clinical values in the differential diagnosis of pleural effusion.