碱性盐酸利多卡因与盐酸利多卡因麻醉作用的比较

Comparative Anesthetic Effects of Lidocaine and Carbonated Lidocaine

对碱性盐酸利多卡因与盐酸利多卡因的麻醉作用进行了比较研究。结果表明碱性盐酸利多卡因的麻醉作用明显强于盐酸利多卡因。其表面麻醉作用为盐酸利多卡因的４倍，浸润麻醉和椎管麻醉作用为盐酸利多卡因的２倍，传导麻醉作用为盐酸利多卡因的６倍，此外与盐酸利多卡因相比，还具有起效快，作用时间长的特点。

The anesthetic effects of lidocaine hydrochloride and carbonated lidocaine hydrochloride were compared.The results of the study showed that the anesthesia of carbonated lidocaine was more potent than that of lidocaine.The topical anesthetic effect of carbonated lidocaine appeared to be four times more potent than that of lidocaine.The infiltration and spinal anesthetic effects and conduction blockade of carbonated lidocaine were two times and six times more powerful than those of lidocaine respectively.In addition,carbonated lidocaine had shorter onset time and longer duration of action,compared with lidocaine hydrochloride.