生物时空振荡分析法

Current Development of Analytical Methods Based on Biological Spatiotemporal Oscillators

一切生物体系本身均存在固有的非线性、非平衡振荡行为。无论是活性酶体系,线粒体体系还是细胞体系都存在许多自组织的时空振荡现象。细胞分析是研究生命过程的切入点,也是现代分析化学研究的前沿和热点。本文评述了以耗散结构为基础,以时空振荡为依托的生物时空振荡分析方法及其特点,重点评述了酶振荡、钙振荡、糖酵解振荡在细胞代谢分析中应用的现状。

Non-linear and non-equilibrium oscillatory behaviors are very common in biological systems, i.e. peroxidase-oxidase reaction, mitochondrion and cell systems. Cell analysis is not only the cut-in point of study on the life process, but also the key subset in modem analytical chemistry. An overview is presented on the analytical method based on dissipation structure and depended on biological spatiotemporal oscillators. The applications of peroxidase-oxidase oscillation, calcium oscillation and glycolytic oscillation on the cellular metabolism assay are summarized.