胸液ADA检测对结核性及癌性胸液的鉴别诊断价值

Value of ADA examination in the distinguish diagnosis of tuberculous and cancerous pleural effusion

目的通过检测结核性胸膜炎及癌性胸液患者胸液中ADA活性,探讨其对鉴别良、恶性疾病的临床意义。方法对77例结核性胸膜炎及79例癌性胸液进行ADA活性检测。结果结核性胸膜炎患者胸液中ADA活性为55.6±16.8u/L,癌性胸液15.5±8.4u/L。前者明显高于后者(P<0.01)。结核性胸膜炎组经有效抗结核治疗后胸液中ADA活性明显下降,而癌性胸液化疗后胸液中ADA活性下降不显。结论检测胸液ADA活性对鉴别良、恶性有较大的帮助。可作为结核性胸膜炎的诊断和鉴别诊断以及疗效观察指标。具有重要的临床实用价值。

Objective To investigate the wdue of ADA examinatian in the distinguish diagnosis of tuberculous and cancerous pleural- effusion. Methods ADA activity was examined in 77 tuberculous pleurisy and 79 cancerous pleural effusinn patients. Results ADA activity was 55.6±16.8u/L in the tuberculous effusiion pntieul.s, while 15.5±8.4u/L in the cancerous ones, The difference between them has statistically signifeanee（P〈0.01）. ADA activity decreased obviously in the tuberculous pleurisy patients after treatment, while not in the cancerous ones. Conclusions ADA examination is very helpful in the, distinguish diagnosis of tuberculous and cancerous pleural effusion.