摘要不安腿综合征(restless legs syndrom e,RLS)的发病机制和病理生理尚未完全明确,但多巴胺类药物治疗该病有良好的效果,其中反跳和症状加重是左旋多巴的主要不良反应。多巴胺激动药不良反应少,已成为治疗该病的主要药物。阿片类、抗惊厥药和苯二氮类药物也是常用的治疗药物。此外,有学者研究发现RLS患者血清铁转移至脑中枢发生障碍,部分RLS患者可通过补充铁剂来治疗。
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