生脉注射液治疗原发性低血压临床观察

Efficacy Treating Essential Hypotension with Shengmai Injection

目的:探讨生脉注射液治疗原发性低血压的疗效及其对血液动力学的影响。方法:采用随机单盲法,将78例原发性低血压患者分为2组,其中40例用生脉注射液治疗作为治疗组,38例以维生素C静脉滴注为对照组,两组均连续用药4周。结果:治疗组的显效率和总有效率分别为45.0%和95.0%;对照组为2.6%和10.5%,两组比较差异非常显著(P<0.01)。生脉注射液治疗后患者收缩压、舒张压、心排出量、心脏指数和射血分数均明显增加,与治疗前比较有非常显著性差异(P<0.01)与对照组比较亦有非常显著性差异(P<0.01)。治疗期间生脉注射液组未见不良反应。结论:生脉注射液是治疗原发性低血压的一种有效而安全的药物。

Objective ： To study the effect of Shengmai Injection （SMI） on essential hypotension and hemody namic. Methods ： Patients（78 cases）with essential hypotension were divided randomly into trial group（40 cases）and control group （38 cases）. The trial group was received SMI for 4 weeks and the control group received Vitamin C injection for 4 weeks therapy in both continuously. Results ：The obvious effective rate and total effective rates were 45% and 95% in trial group repeetively, they were higher than those in control group（2.6% and 10.5% ） ,there was obvious difference between the 2 groups（ P 〈 0.01 ）. At the same time, systolic blood pressure （ SBP）, diastolic blood pressure （ DBP）, cardiac output （ CO）, cardiac index （ CI）, and ejection fi action （EF） could be signifi- cantly increased（ P 〈 0.01 ）. After the treatment of SMI. in trial group were superior to those in control group （ P 〈 0.01 ）. Canclusion ：SMI is an effective and safe drug for treating essential hypotesion.