摘要
根据阿尔茨海默病发病机理的胆碱能假说及其最新的生理及病理学研究结果,对现有临床治疗阿尔茨海默病的乙酰胆碱酯酶抑制剂药物的特点及应用进行了概括和总结;根据中医药治疗老年痴呆及有关研究的现状,特别通过一些中药经体外酶抑制活性实验结果,论述从中草药活性成分开发新型治疗阿尔茨海默病抑制剂药物的趋势、方向及必要性和可行性。
According to the suppositions on disease function of Alzheimer＇ s disease（AD） and it＇s new research results of physiology and pathology ,the characteristic and application of acetylcholinesterase inhibitors for treating AD in clinic were surveyed. In conjuction with present coditions of curing AD by traditional Chinese medica and basease on the test results of inhibit - acetylcholinesterasc out - body, the feasibility and necessity for develop new AD drugs of acctylcholinesterasc inhibitors from active constituents in Chinese herb medicines were recommended.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2006年第1期19-20,共2页
Lishizhen Medicine and Materia Medica Research
基金
西南科技大学重大科技研究项目资助(No.ZK033129)
关键词
阿尔茨海默病
胆碱酯酶抑制刑
中草药
中医药
活性组分
Alzheimer＇ s disease （ AD ）
Acetylcholinesterase inhibitors
Chinese herb medicines
Traditional Chinese medica
Active constituents
