氯化锌催化合成二异亚丙基-D-甘露醇

Synthesis of Diisopropylidene-D-mannitol Catalyzed by Zinc Chloride

以甘露醇为原料，氯化锌作催化剂合成二异亚丙基-D-甘露醇，考察了影响反应的因素，结果表明反应的最佳条件为：n（D-甘露醇）：n（丙酮）：n（氯化锌）=1：21．4：1．85，反应温度为30～35℃，反应时间12h，产率可达62．8％。

Diisopropylidene-D-mannitol was synthesized using D-mannitol as raw material and zinc chloride as catalyst. The factors influencing on reaction were investigated. The optimum reaction conditions were as follows：the molar ratio between D-mannitol,acetone and zinc chloride was 1：21. 4： 1.85, the reaction temperature was 30 - 35℃ , reaction time was 12h,and 62. 8% of yieht was achieved.