年龄和性别与冠状动脉钙化、狭窄的相关性分析

Age and gender correlation analysis between coronary artery calcification and stenosis

目的:探讨年龄和性别与冠状动脉钙化(CAC)及冠状动脉狭窄的相关关系,以及年龄和性别对CAC 诊断冠心病(CHD)的影响。方法:记录591例可疑CHD患者临床相关指标,对所有入选患者行冠状动脉造影, 分析年龄和性别与冠状动脉钙化、狭窄的相关关系。结果:CAC总检出率为43．82％,其中男性和女性患者CAC 检出率分别为42．32％和49．14％,差异无统计学意义。60岁以下男性患者CAC检出率高于女性,但60岁以上女性钙化检出率已超过男性。检出冠脉狭窄患者433例,占入选患者总数的73．27％,其中男性和女性患者狭窄检出率分别为76．84％和58．62％,差异有统计学意义(P<0．05)。各年龄组的狭窄检出率男性均高于女性,但60岁以上女性狭窄检出率迅速增高。结论:年龄和性别对冠状动脉钙化诊断冠心病的价值有很大影响,临床上评价冠状动脉钙化对冠心病的诊断时必须充分考虑年龄和性别因素。

Objective： To investigate the influence of age and gender on the coronary artery calcification （CAC） and stenosis and on the value of CAC for diagnosing coronary heart disease （CHD）. Methods. 591 in patients were recorded their history and clinical index and examined by selective angiography. The correlation of age and gender with CAC and stenosis were assessed and compared. Results： The total prevalence of CAC was 43.82%. Men and women CAC rate were 42.32 %and 49.14%, respectively. Before 60 years, the CAC rate was higher in men than women. 433 patients were discovered stenosis. The total of coronary artery stenosis rate was 73.27%, whereas it was 76.84% in men and 58.62% in women. The difference between genders had significant. In different age groups, the ments coronary artery stenosis rate was higher than womenrs. Form 60, the womenrs stenosis rate was increased and got close to the same aged men. Conclusions： The coronary artery calcification is aggravated with aging. In general, the cAc rate in women is less than in men of the same age group. After 60 years, the women＇s CAC rate have a phenomenon of rapidly increase, and the CAC rate in women was beyond men＇s. Age and gender have great effect on the value of coronary calcium for diagnosis of CHD. The factors, age and gender, must be sufficiently considered while CHD was diagnosed according as CAC.