应用十六层螺旋CT测定冠状动脉钙化积分的可靠性研究

Study on the reliability on the determination of coronary artery calcification score with sixteen-layer spiral computed tomography

目的研究十六层螺旋CT测定冠状动脉钙化积分的可靠性。方法54名观察对象皆连续进行两次十六层螺旋CT扫描,每次扫描结果分别独立由两名放射科医生测定其冠状动脉钙化积分。结果两次扫描结果间存在高度一致性;Pearson相关系数为0.998(医生1)和0.997(医生2),Spearman相关系数为0.995(医生1)和0.996(医生2);经统计学检验,相关系数均具有显著意义(P<0.001);而且两次扫描结果间差值的绝对值均集中在50以内,占90.7%(医生1)和85.2%(医生2)。两位放射科医生阅片结果间也存在高度一致性;Pearson相关系数为0.999(扫描1)和0.998(扫描2),Spearman相关系数为0.997(扫描1)和0.998(扫描2);经统计学检验,相关系数也均具有显著意义(P<0.001),并且他们阅片结果间差值的绝对值也集中在50以内,分别占77.8%(扫描1)和92.6%(扫描2)。结论尽管十六层螺旋CT在测量冠状动脉钙化积分高的观察对象时有较高的变异性,但在十六层螺旋CT测定冠状动脉钙化积分还是可以重复的。因此,没有必要在相同位置对患者进行两次扫描。

Objective To explore the reliability of 16 - layer spiral computed tomography in determination of coronary artery calcium scores. Methods Fifty - four subjects were scanned two times with 16 -layer spiral computed tomography and the coronary artery calcium scores were determined after independently noted down by X - ray doctors after each scanning. Results There high consistency was observed in the results obtained between two scans, The Pearson correlation coefficients were 0,998 （for the first doctor） and 0.997 （for the second one）. The Spearman correlation coefficients were 0.995 （for the first doctor） and 0.996 （for the second one）, showing significant （ P 〈 0.001 ）. Besides the majority of continuous data interscan differences were less than 50. Furthermore the differences of a majority of inter - reader were less than 50 for scan 1 and 2. Conclusion It is reproducible in determination of coronary artery calcium scores using 16 - layer spiral computed tomography, thus there is no need to perform two scans at the same site of the patients.