肺转移性印戒细胞癌1例并文献复习

Analysis of pulmonary metastatic signet ring cell carcinoma patient with literature review.

目的通过该解剖病例结合相关文献的复习,研究胃转移性肺肿瘤引起呼吸衰竭的原因。方法对死亡病例进行尸体解剖,采用光镜、特殊染色及免疫组化,光镜下观察各脏器的病理变化。结果双肺散在分布多量大小不等肿瘤细胞转移灶,原发病灶为胃小弯侧一直径0.5cm×1.0cm大小的溃疡状癌灶,肿瘤细胞黏液染色阳性。结论病人因患有恶性度极高的黏液细胞型胃癌,转移到肺,至肺泡被大面积填塞及肺泡结构破坏,呼吸面积大大减少,引起呼吸衰竭而死亡。

Objective To investigate the cause of acute respiratory failure due to metastasis of pulmonary carcinoma from stomach to lungs by analysis of dissection results and review of relevant literatures. Methods The death case was dissected and the pathologic changes in each organ by were observed under light lens after stained with special and histochemical staining. Results There were metastasis loci in the lungs diffused with many tumour cell of various size. The primary focus was an anabrolic carcinoma in arcus minor ventriculi with diameter of 0.5×1.0cm, the sticky liquid in tumor cell gave positive results after stained. Conclusion The stomach carcinoma patient died of respiratory failure due to metastasis and trauma of the lungs, lung alveolus in a large area.