手性2-(口恶)唑烷酮的无溶剂合成法

Synthesis of Evans' 2-Oxazolidinone Under Solvent-free Conditions

在无溶剂条件下,手性的β-氨基醇和脲在160-180℃反应0．5-1 h,在200℃反应0．5 h,高产率地获得手性噁唑烷酮。

Aminoalcohols reacted with urea at 160 - 180℃ for 1 h and at 200 % for 0. 5 h without solvent to give chiral 2-oxazolidinones in high yields.