痛经贴质量标准研究

Study on Quality standard of tongjingtie

目的：建立痛经贴的质量标准。方法：对延胡索乙素和冰片进行了薄层色谱（TLC）鉴别。用高效液相色谱法（HPLC）测定了痛经贴中延胡索乙素的含量。结果：薄层色谱斑点清晰；延胡索乙素在0．0187～0．093mg·ml^-1范围内，对照品浓度与峰面积呈良好线性关系，r=0．9999，平均加样回收率为98．80％，RSD为0．97％。结论：方法简便、准确、重现性好、精密度高。可用于控制痛经贴的质量。

Objective：To establish the quality standard for Tong- jingtie. Methods：Tetrahydropalmatine and Borneolum synthetieum were identified by TLC,and the eontent of Tetrahydropalmatine was determined by HLPC. Results：The TLC spos developed was fairly clear. A good linearity of Tetrahydropalmatine was obtained（ r = 0.9999） within the range of 0. 0187 - 0. 0933mg·ml^-1. The average recovery of Tetrahydropalmatine was 98, 80% ,RSD = 0.97%. Conclusion ：The method is simple, accurate and of good repeatability and high precision . The method can be used for the quality control of Tongjingtie.