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清道夫受体A与动脉粥样硬化 被引量：1

Scavenger Receptor-A and Atherosclerosis
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摘要 氧化修饰低密度脂蛋白在动脉粥样硬化的发生发展过程中起重要作用。介导氧化修饰低密度脂蛋白的受体种类繁多,尤其是清道夫受体A。本文就近年来有关该受体的结构、分布、调节、配体及其在动脉粥样硬化中的作用的研究作一阐述,以便进一步了解动脉粥样硬化的发生机制,探索防治途径。 The oxidized low density lipoprotein plays an important role in the origin and development of Atherosclerosis. There are many types of receptors secreted the oxidized low density lipoprotein, especially scavenger receptor A .The structure,distribution.regulation,ligend and function will be elaborated in this article,to find out the mechanism of Atherosclerosis and to explore the way of prevention and treatment.
作者 秦珍珍 于晓玲
机构地区 辽宁省锦州医学院附属第一医院心血管病诊治中心
出处 《医学综述》 2006年第1期13-15,共3页 Medical Recapitulate
关键词 受体 清道夫 动脉粥样硬化 低密度脂蛋白 Receptor, scavenger Atherosclerosis Low density lipoprotein
分类号 R543.5 [医药卫生—心血管疾病]
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参考文献19

  • 1Krieger M, Heiz J. Structures and functions of multiligand lipopretein receptors: macrophage scavenger receptors and LDL receptor related protein (LRP) [ J]. Annu Rev Biochem, 1994,63 (6) : 601-637.
  • 2Linton MF, Fazio S, Class A scavenger receptors, macrophage, and atherosclerosis[J]. Curr ODin Lipidol,2001,12(5) :489-495.
  • 3Coller SP, Paulnock DM. Signaling pathways initiated in maerophages after engagement of type A scavenger receptors[J]. Leukoc Biol,2001,70(1):142-148.
  • 4Guidcz F, Li AC. Horvai A, et al. Differential utilization of Ran signaling pathways by macrophage colony-stimulating factor(CSF)and granulocytc-macrophage CSF receptors during macrophage differentiation[ J].Mol Cell Biol, 1998,18(7) :3851-3861.
  • 5Moore K J, Rosen ED, Fitzgerald ML, et al. The role of PPAR-ganuna in macrophage differentiation and cholesterol uptake[J], Nal Med, 2001,17(1) :41-47.
  • 6金艳,陈琪,魏恩会,蒋莉,范乐明,王南,陈秀英.酪氨酸蛋白激酶抑制剂genistein对PMA处理后A类清道夫受体表达的抑制[J].生物化学与生物物理学报,2001,33(1):142-146. 被引量：6
  • 7Winther MPJ, Dijk KWV, Havekes LM, et el. Macmphage scavenger receptor class A: a mu]tifunctional receptor in athemsclerosis[J]. Arterioscl Throm Vas,2000,20(2):290-297.
  • 8Bobbins AK, Horlick BA. Maerephage scavenger receptor confers and adherent phcnotype to cells in cuhurel [J]. Biotechniques, 1998,25(2) :240-244.
  • 9Van Velzen AG, Suzuki H, Kodama T, et al. The role of scavenger receptor class A in the adhesion of cells is dependent on cell type and cellular activation state [ J ]. Exp Cell Res, 1999,230 ( 1 ) : 264-271.
  • 10Santiago Garcia J, Kodama T, Pitas RE. The class A scavenger receptor binds to proteoglycans and mediates adhension of macrophages to the extracdlular matrix [ J ]. Biol Chem, 2003,278 ( 9 ) : 6942-6946.

二级参考文献11

  • 1[1]Suzuki H, Jishage K. Physiological roles of macrophage scavenger receptor type A Ⅰ/Ⅱ in vivo[J]. Seikagaku, 2001, 73(3): 183-186.
  • 2[2]Suzuki H, Kurihara Y, Takeya M, et al. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection[J]. Nature, 1997, 386(6622): 292-296.
  • 3[3]Van Berkel, Van Velzen, Kruijt J, et al. Uptake and catabolism of modified LDL in scavenger-receptor class A type Ⅰ/Ⅱ knock-out mice[J]. Biochem J, 1998, 331(Pt 1): 29-35.
  • 4[4]Sakaguchi H, Takeya M, Suzuki H, et al. Role of macrophage scavenger receptros in diet-induced atherosclerosis in mice[J]. Lab Invest, 1998, 78(4): 423-434.
  • 5[5]Suzuki H, Kurihara Y, Takeya M, et al. The multiple roles of macrophage scavenger receptors (MSR) in vivo: resistance to atheroscleosis and susceptibility to infection in MSR knockout mice[J]. J Atheroscler Thromb, 1997, 4(1): 1-11.
  • 6[6]Ling W, Lougheed M, Suzuki H, et al. Oxidized or acetylated low density lipoproteins are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A type Ⅰ/Ⅱ gene[J]. J Clin Invest, 1997, 100(2): 244-252.
  • 7[7]Lougheed M, Lum CM, Ling W, et al. High affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type Ⅰ/Ⅱ[J]. J Biol Chem, 1997, 272(20): 12938-12944.
  • 8Loren G，J Biol Chem，1999年，274卷，36808页
  • 9Jin Y，生物化学与生物物理学报，1999年，31卷，395页
  • 10Hsu H Y，J Biol Chem，1998年，273卷，1240页

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医学综述
2006年 第1期

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