糖调节受损再认识及其与炎症的关系

Recognition of Impaired Glucose Regulation and the Relationship between It and Inflammation

糖调节受损是介于正常血糖与糖尿病之间的一种代谢异常状态。在糖调节受损者血浆中多种炎性因子明显升高,炎性因子可以引起胰岛素抵抗和胰腺β细胞凋亡。降低血清炎性因子水平和减轻胰岛素抵抗的药物能明显影响糖调节受损的转归。

Impaired glucose regulation is a kind of abnormal metabolism state between normal plasma glucose and diabetes mellitus. The inflammatory factors which can cause insulin resistance and apoptosis of islet beta cell are significantly increased in the serum of subjects with impaired glucose regulation. The drugs which can lower inflammatory factors level in serum and relieve insulin resistance will obviously influence the turnover of impaired glucose regnlation.