摘要
在临床上冠心病的无创性诊断方法有多种,就负荷心肌灌注显像而言,包括了运动负荷和药物负荷,本文对各方面资料的综合分析后认为腺苷通过其多方面的作用机制引起冠脉的扩张,是其核素心肌显像的基础,并且由于其副作用少,作用时间短,诊断敏感性和特异性均较高而在临床上被认为是诊断冠心病的最可靠的无创性方法,但就腺苷与不同的心肌显像剂结合(99mTcsestimib和99mTcTetrofosmin)是否能更好的提高诊断率有待论证。
Thero are a lot of noninvasive methods to diagnose coronary heart disease,In terms of the stressfull myocardial perfusion imaging, it indudes exercise test and pharmacological test. According to analyze a lot of materials it believes adenosine lead to dilate coronary artery through some mechanism and that is the basis of myocardial perfusion imaging. Moreover, adenosine have a little side effect and shot half-life and high sensitivity and speciality. So it is thought clinically the most reliable noninvasive diagnosing method. Wether adenosine combined with different imaging agent(Tc99m-sestimibi and Tc99m -Tetrofosmin) can improve the diagnostic rate in myocardial perfusion imaging,it is discussed in the future.
出处
《医学综述》
2006年第2期122-124,共3页
Medical Recapitulate
关键词
冠心病
腺苷负荷试验
心肌
灌注
局部
Coronary heart disease
Stressful adenosine test
Myocardium
Perfusion, regional