五指牛奶化学成分的研究

Chemical constituents from roots of Ficus hirta

目的:研究五指牛奶Ficus hirta的化学成分。方法:采用反复硅胶柱色谱进行分离纯化,根据理化性质和光谱数据进行结构鉴定。结果:得到10个化合物,分别为β-谷甾醇(1),豆甾醇(2),补骨脂素(3),3β-羟基豆甾-5-烯-7-酮(4),5-羟基-4′,6,7,8-四甲氧基黄酮(5),4′,5,6,7,8-五甲氧基黄酮(6),芹菜素(7),β-香树素乙酸酯(8),α-香树素乙酸酯(9),橙皮苷(10)。结论:化合物4,5,6为首次从该属植物中分离得到,其他为首次从该植物中获得。

Objective： To study the chemical constituents from the roots of Ficus hirta. Method： Compounds were isolated by chromatographic techniques on silica gel and HP-20 resin columns. Their structures were elucidated by chemical and spectroscopic methods. Result： Ten compounds were identified as β-sitosterol （1）, stigma.sterol （2）, psoralene （3）, 3β-hydroxy-stigmast-5-en-7-one （4）, 5-hydroxy- 4＇, 6, 7, 8-tetramethoxy flavone （5）, 4＇, 5, 6, 7, 8-pentamethoxy flavone （6）, 4＇, 5, 7-trihydroxy-flavone （7）, 3βacetoxy-β-amyrin （8）, 3β-aeetoxy-α-amyrin （9） and hesperidin （10）. Conclusion： The compounds 4, 5, 6 were obtained from this genus for the first time, and all the compounds were obtained from this plant for the first time.