陕西麟游大骨节病病区可疑致病因素的logistic回归分析

Logistic regression of the environmental risk factors in areas with Kashin-Beck disease

目的分析大骨节病病区家庭可疑致病因素的暴露情况,寻找不同类型病区内影响大骨节病患病的因素。方法采用logistic回归对轻、中、重三种类型病区的可疑致病因素进行分析,并比较不同类型病区内可疑致病因素的差异。结果单因素分析发现,卫生状况和肉蛋奶在各类型病区内均显示与患病有关。多因素logistic分析发现不同类型病区内影响患病的因素不同,轻病区为小麦、中病区为卫生状况和肉蛋奶、重病区是卫生状况、大米和肉蛋奶。结论影响患病的因素与病区类型有关,针对不同病区类型采取不同的预防措施有望进一步提高预防效果。

Objective In order to find the factors influencing the prevalence of KBD, the possible nosogenetic factors of the family in Kashin-Beck disease （KBD） areas were analyzed. Methods The possible nosogenetic factors in mild, middle, high prevalence KBD areas were analyzed by logistic regression. The differences of the factors between three kinds of KBD areas were compared. Resets Univariate analysis found sanitary conditions and meat-egg-mild were associated with KBD prevalence in all kinds KBD areas. Binary logistic analysis of multivariate suggested the possible nosogenetic factors were different in the different kind of KBD areas. It was wheat in mild prevalence area, sanitary conditions and meat-egg-mild in middle prevalence area, and sanitary conditions, rice and meat-egg-mild in high prevalence area. Conclusion The risk factors are associated with the kind of KBD areas. The different preventive methods should be taken according to the kind of KBD areas, which will improve the effect of prevention.