血清CA199检测对子宫内膜异位症的诊治意义

To Study the Significance in Endometriosis Diagnosis by Determination of Serum CA199

目的探讨检测血清CA 199对子宫内膜异位症的诊断及病情严重程度判断的指导意义,验证检测血清CA 125对该病辅助诊断的有效性。方法应用微粒子发光方法检测110例子宫内膜异位症患者血清CA 199和CA 125指标,并将110例患者依术中所见按AFS[1]分期分成Ⅰ、Ⅱ、Ⅲ、Ⅳ四组;按有无并发症和有无其他妇科疾病分别加以研究。结果AFS分期越高CA 199水平越高。结论CA 199可提示子宫内膜异位症的严重程度,对子宫内膜异位症的诊治有参考价值。

Objective To study the significance in endometriosis diagnosis and in consideration of severeness by determination of serum CA199 level ,and to prove the efficiency of serum CA125 detection to the endometriosis diagnosis. Methods The serum CA125 and CA199 level in 110 patients with endometriosis were measured by microparticle enzyme immunossay. Divide the 110 patients into four groups according to the surgical pathologic representation and AFS staging,and study the CA199 results respectively depending on the complication and other gynecological disease. Results The patients group with higher AFS staging,are higher in serum CA199 detection. Conclusion The serum CA199 level can indicate the severeness of endometriosis,and may be a useful reference method for the endometriosis diagnosis.