摘要
在高氯酸镉存在下,通过2-氨基乙基-二(3-氨基丙基)胺与2,6-二甲酰基-4-R-苯酚的[2+3]席夫碱缩合反应制备了6种穴合物[Cd2Ln](当R=CH3,CH3O,C(CH3)3,F,C l,B r,n为1、2、3、4、5、6)。[Cd2L1]在溶液中的不完全水解反应产生了1个新的双核Cd(Ⅱ)穴合物[Cd2Lh]。通过元素分析、红外光谱、电子光谱、电喷雾质谱等分析手段对以上7种Cd(Ⅱ)穴合物进行了谱学表征,并利用细菌作为指示生物测定了抑菌毒性。结果表明,上述穴合物对受试菌种,尤其是金黄色葡萄球菌,都表现出较强的抑菌毒性作用。
Six bicadmium（ Ⅱ ） cryptates [ Cd2L^n ] were synthesized by the [ 2 ＋ 3 ] Schiff base condensation of 2-aminoethyl-bi （ 3-aminopropyl ） amine with sodium 2, 6-diformyl-4-R-phenolate （ R = CH3, CH3 O, C（ CH3 ） 3,F,Cl, Br, n = 1,2,3,4,5,6, respectively） in the presence of Cd^2＋. After one imine group of [ Cd2L^1] was hydrolyzed and solvent addition, with no ring opening, cryptate [ Cd2 L^h] was produced. The structures of the seven complexes were confirmed by elemental analysis, IR, electronic spectrum, and ES-MS. The toxicities of the complexes were evaluated by testing antimicrobial activity against bacterial strains. The complexes were active against four organisms tested with no exception, showing highest antimicrobial activity against staphyloccus aureus.
出处
《应用化学》
CAS
CSCD
北大核心
2006年第2期173-178,共6页
Chinese Journal of Applied Chemistry
基金
江苏省普通高校高新技术产业发展项目(JHB05-51)资助项目
