U形管引流用于晚期肝门部胆管癌25例疗效分析

Clinical Application and Efficacy of U-Tubes for Late Stage Hilar Cholangiocarcinoma

目的分析评价U形管引流对不能手术切除的肝门部胆管癌的临床疗效及应用价值．方法对1995-2003年收治的25例不能切除的肝门部胆管癌，行U形管引流术。结果25例手术经过顺利，总胆红素从术前的（307．9±164．8）mmol／L下降为术后的（180．1±83、8）mmol／L血清转氨酶从术前的（132．2±41．9）U／L下降为（51．9±15．3）U／L。22例获随访病人平均存活时间为15．3个月，有2例已存活4年。结论不能手术切除的肝门部胆管癌病人行U形管引流可有效地解除黄疸，改善肝功能，提高病人的生存质量，延长存活期。

Objective The recent experience with U-tubes was reviewed in order to assess their clinical value for late stage hilar cholangiocarcinoma. Methods The hospital charts of all patients with unresectable hilar cholangioearcinoma who had U-tubes placed between 1995 and 2003 were reviewed retrospectively. Results All operations were performed successfully. The mean TBIL levels dropped from （307.9 ± 164.8） mmol/L to（ 180. 1±83.8） mmol/L and the mean ALT levels dropped from （ 132. 2 ±41.9）U/L to（51.9 ±15.3 ）U/L. The mean survival time of 22 patients who were followed up was 15.3 months and 2 patients had survived 4 years. Conclusion The use of U-tubes could relieve biliary obstruction and improve hepatic function, so it was advocated in the patients with unresectable hilar cholangioearcinoma.