摘要
作者为阐明食管癌术后放疗的效果,将1985~1989年期间82例食管癌术后预防性放疗病人与同期982例单纯手术病人进行对比观察。手术采用食管次全切除加食管周围脂肪组织和淋巴结、以及贲门、胃左淋巴结切除。放疗在术后2~6周开始,剂量为纵隔区50~60Gy/5~6周,双锁骨上区50Gy/5周。结果表明,Ⅱa期术后放疗病人5年生存率为42.0%,单纯手术组为26.0%(P<0.01)。Ⅲ期病人的5年生存率两组无差异(P>0.05),但术后放疗组逐年生存率略高于单纯手术组。结果提示,除0期病人外,食管癌术后均应进行放疗。
In order to clarify the effect of radiation therapy following resection of esophageal carcinoma,a comparative study was done between the group of 82 patients treated by this method and the group of 982 patients treated by operation only during l985 to l989.The operation was subtotal resection of esophagus with additional resections of paraesophageal fat tisstie and l ymph nodes,and lymph nodes around the gastric cardia and left gastric lymph nodes.Radiation therapy began at from 3rd to 6th weeks after operation and the dose was 50 ̄ 60 Gy/5 ̄6W in mediastinal region,50 Gy/5W in supraclavicular areas,The results showed that 5- year survival rate of the patients treated by operation with postoperative radiothrapy and by operation only were 42.0% and 26.0%(P<0.0l)respectively in stage IIa.Of the patients in stage Ⅲthe postoperative survival rate was little higher in the group of patients treated by operation with postoperative radiotherapy than in the patients treated by operation only.but there was no significant difference between the two groups(P>0.05).It is suggested that postoperative radiotherapy should be carried out in all patients with esophaged cancer in the any stages except the patients in stage 0.
出处
《实用癌症杂志》
1996年第3期182-184,共3页
The Practical Journal of Cancer
关键词
食管癌
外科手术
手术后
放射疗法
Esophageal tumour Cancer Operation Postoperative radiotherapy