摘要
目的探讨蒙古族高血压人群血管紧张素转换酶(ACE)基因I/D多态性与胰岛素抵抗及血脂的关系。方法选择115例高血压者和114例血压正常者检测血脂、血糖和胰岛素水平;分析高血压组ACE基因I/D多态性与胰岛素抵抗及血脂的关系。结果在高血压组及正常对照组中,未发现ACE基因I/D多态性胰岛素抵抗及血脂有关联(P>0.05)。结论蒙古族高血压人群中ACE基因I/D多态性与胰岛素抵抗及血脂水平无关联。
Objective To explore the association between angiotensin-converting enzyme（ACE）gene I/D polymorphism and insulin resistance and blood lipid in Mongolian hypertensives. Methods 115 Mongolian hypertensives and 114 Mongolian normotensives were selected to test blood lipid, blood glucose and insulin; analyzing examining the insertion/deletion polymorphism of ACE gene in hypertensives and normotensives. Results These was no significant difference to be found between ACE gene I/D polymorphism and insulin resistance and blood lipid in Mongolian hypertensives and normotensives （ P 〉 0.05）. Conclusion The ACE gene polymorphism was not related to insulin resistance and blood lipid in Mongolian hypertensives.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2006年第2期147-148,共2页
Chinese Journal of Public Health
基金
国家自然科学基金(30040040)
