摘要
醛甾(固)酮与其受体结合后通过增加水钠潴留加重高血压。醛甾酮拮抗药分为选择性和非选择性2 大类。醛甾酮受体拮抗药不仅有助于降低血压,而且可减少醛甾酮对心血管系统的不利作用,减少心室肥厚和心血管事件的发生率。
The combination of aldosterone and its receptor leading to increase of sodium and water retention aggravate hypertension. Aldosterone receptor antagonist may divide to two types: selective and nonselective, not only help to reduce blood pressure, but also decrease the adverse cardiac-vascular effects of aldosterone, cardiac venticular hypertrophy and occurrence of cardiac-vascular events.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2006年第2期136-139,共4页
Chinese Journal of New Drugs and Clinical Remedies