瑞芬太尼复合依托咪酯麻醉诱导下气管插管的血流动力学变化

Hemodynamic changes after anesthesia induction with remifentanil

目的对比瑞芬太尼复合依托咪酯麻醉诱导与芬太尼复合依托咪酯麻醉诱导后气管插管血流动力学的变化。方法40例患者分为瑞芬太尼组与芬太尼组,诱导后2min行气管插管术。分别记录诱导前、诱导后1min及插管后2min的平均动脉压(MAP)和心率(HR)。插管条件由操作者给予评分。结果两组诱导后MAP和HR较诱导前均下降,差异有统计学意义(P<0.05)。插管后两组间的MAP差异有统计学意义(P<0.05)。结论瑞芬太尼复合依托咪酯麻醉诱导在抑制插管引起的心血管反应方面瑞芬太尼组优于芬太尼组。

Objective To assess the intubating hemodynamic changes after anesthesia induction with etomidate and remifentanyl or fentanyl. Methods Forty patients were allocated into 2 groups. After induction,tracheal intubation was performed 2 minutes later. Mean arterial pressure（MAP） and heart rate（HR） were measured before anesthesia induction, 1min after induction, 2min after induction. Results The MAP and HR after induction were lower than baseline （P〈0.05）. After intubation, MAP was significantly different between 2 groups（P〈0.05）. Conclusion The control of cardivascuiar responses to tacheal intubation with remifentanyl is more effective than that with fentanyl.