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替罗非班在急性冠脉综合征介入术后无复流患者中的应用 被引量:11

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摘要 将31例急性冠脉综合征(ACS)行介入术后无复流患者随机分为替罗非班组和对照组进行治疗,观察用药后两组心电图、血小板聚集率、主要终点事件发生率及冠脉造影(CAG)前向血流的情况。结果显示,与对照组相比较治疗组心电图ST段明显改善,缺血损伤导联减少;血小板聚集率明显降低;主要终点事件发生率显著下降;CAG前向血流T IM I分级明显提高(P均<0.05)。提示替罗非班可抑制血小板聚集,促进微血管灌注,明显改善ACS患者介入术后无复流现象。
出处 《山东医药》 CAS 北大核心 2006年第1期48-49,共2页 Shandong Medical Journal
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  • 1Platelet receptor inhibition in ischemic syndrome management(PRISM) study investigators. A comparison of aspirin plus tirofiban with aspirin plus heprin for unstable angina. N Engl J Med, 1998, 338:1498-1505.
  • 2The PRISM-PLUS Study Investigators. Inhibition of the platelet glycoprotein Ⅱ b/Ⅲ a receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction.N Engl J Med,1998,338:1488-1497.
  • 3The RESTORE Investigators. Effects of platelet glycoprotein Ⅱ b/Ⅲ a blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. Circulation, 1997,96:1445- 1453.
  • 4Kloner RA,Ganote CE,Jennings RB.The "no-reflow" phenomenon after tempo-rary coronary occlusion in the dog[J].J Clin Invest,1974,54:1496-1508.
  • 5Piana RN,Paik GY,Moscucci M,et al.Incidence and treatment of 'no-reflow' after percutaneous coronary intervention[J].Circulation,1994,89:2514-2518.
  • 6Abbo KM,Dooris M,Glazier S,et al.Features and outcome of no-reflow after percutaneous coronary intervention[J].Am J Cardiol,1995,75(12):778-782.
  • 7Weyrens FJ,Mooney J,Lesser J,et al.Intracoronary diltiazem for microvascular spasm after interventional therapy[J].Am J Cardiol,1995,75:849-850.
  • 8Assali AR,Sdringola S,Moustapha A,et al.Percutaneous intervention in saphenous venous grafts:in-stent restenosis lesions are safer than de novo lesions[J].J Invasive Cardiol,2001,13(6):446-450.
  • 9Watson PS,Hadjipetrou P,Cox SV,et al.Angiographic and clinical outcomes fol-lowing acute infarct angioplasty on saphenous vein grafts[J].Am J Cardiol,1999,83(7):1018-1021.
  • 10Yip HK,Chen MC,Wu CJ,et al.Clinical features and outcome of coronaryartery aneurysm in patients with acute myocardial infarction undergoing a primary per-cutaneous coronary intervention[J].Cardiology,2002,98(3):132-140.

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