摘要
从海洋生物中提取海藻酸纳和壳聚糖作为纳米粒的包被材料,并分别包装成人胰岛素纳米粒。选用基质辅助激光解吸离子化飞行时间(Matrix-assistedlaserdesorptionionization/timeofflight,MALDI-TOF)质谱技术研究胰岛素海藻酸钠纳米粒包装、释放过程及在不同酸碱介质条件下的稳定性。
Sodium alginate and chitosan extracted from the halobios were selected as packaging materials of nanoparticles of the human insulin nanoparticles, respectively. Matrix-assisted laser desorption ionization/time of flight （MALDI-TOF） mass spectrometry was used to study the processes of packaging and releasing of the insulin and its stability in the different basic and acidic mediums from the sodium alginate nanoparticles.
出处
《海洋科学》
CAS
CSCD
北大核心
2006年第1期73-77,共5页
Marine Sciences
基金
国家自然科学基金资助项目(0402760633)
福建省自然科学基金资助项目(C0310006)
