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NKT细胞在抗肿瘤免疫中的作用及其机制 被引量：5

Functional role of natural killer T cells and their mechanisms in anti-tumor immunity
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摘要 NKT细胞是免疫细胞中一类具有NK细胞特定标志的T细胞亚群,经活化,既可直接作为抗肿瘤效应细胞发挥杀伤作用,又能通过激活其他免疫效应细胞,如NK细胞,间接实现抗肿瘤作用。NKT细胞在抗肿瘤免疫、获得性免疫应答及免疫调节中起着重要作用。 Natural killer T （NKT） cells are a population of T cells that share some characteristics with natural killer （NK） cells. After activated, NKT cells can kill tumors directly as the anti-tumor effectors and they can also activate other cell types, such as NK cells, to mediate anti-tumor effects indirectly. NKT cells play an important role in anti-tumor immunity, adaptive immune responses and immunoregulation.
作者 杨洁 范华骅 章平 高峰
机构地区 上海市血液中心血液工程研究室 华东师范大学生命科学学院分子免疫研究室
出处 《生命科学》 CSCD 2006年第1期62-66,共5页 Chinese Bulletin of Life Sciences
基金 上海市自然科学基金(012B14057 002B14053)
关键词 NKT细胞 抗肿瘤作用 抗肿瘤机制 NKT cells anti-tumor function anti-tumor mechanism
分类号 R392.12 [医药卫生—免疫学] R730.3 [医药卫生—肿瘤]
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生命科学
2006年 第1期

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